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Synthesis, cytotoxicity and in vitro antileishmanial activity of naphthothiazoles
(2013-06-01)
The leishmaniasis is a spectral disease caused by the protozoan Leishmania spp., which threatens millions of people worldwide. Current treatments exhibit high toxicity, and there is no vaccine available. The need for new ...
Cytotoxic and apoptotic effects of leptocarpin, a plant-derived sesquiterpene lactone, on human cancer cell lines
(Elsevier Ireland Ltd, 2015)
An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex
(SAGE PUBLICATIONS LTD, 2010)
Anti-obesity medications deserve special considerations at the present time due to an increasing number of overweight and obese people who require these therapeutic alternatives. Obesity is positively associated with several ...
Bioactive guanidine alkaloids from Pterogyne nitens
(1995-12-01)
Bioactivity-guided fractionation of a methanolic CHCl 3 extract of the leaves of Pterogyne nitens afforded the known guanidine alkaloid pterogynidine [2] and three new guanidine alkaloids, nitensidines A [3], B [4], and C ...
Bioactive guanidine alkaloids from Pterogyne nitens
(1995-12-01)
Bioactivity-guided fractionation of a methanolic CHCl 3 extract of the leaves of Pterogyne nitens afforded the known guanidine alkaloid pterogynidine [2] and three new guanidine alkaloids, nitensidines A [3], B [4], and C ...
A new cytotoxic naphthopyrone dimer from Paepalanthus bromelioides
(2000-09-01)
A new naphthopyrone dimer was isolated from the capitula of Paepalanthus bromelioides by chromatographic procedures. Its structure was deduced from spectrometric data. On colorimetric assay for cytotoxicity the new dimer ...
A new cytotoxic naphthopyrone dimer from Paepalanthus bromelioides
(2000-09-01)
A new naphthopyrone dimer was isolated from the capitula of Paepalanthus bromelioides by chromatographic procedures. Its structure was deduced from spectrometric data. On colorimetric assay for cytotoxicity the new dimer ...
Efectos de drogas citotóxicas sobre células HEp-2 y U-937
(Universidad de Belgrano. Facultad de Ciencias Exactas y Naturales. Carrera de Ciencias Biológicas, 2005)
El objetivo del presente estudio fue analizar en forma comparativa distintos métodos para determinar muerte celular, paso previo a su aplicación en la investigación de nuevas drogas o procedimientos citotóxicos. Se eligió ...
Ascorbic acid potentiates the cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin
(Pergamon-Elsevier B.V. Ltd, 2008-08-01)
The interaction of ascorbic acid with 5-methoxy-3,4-dehydroxanthomegnin, an 1,4-naphthoquinone, was investigated using the cytotoxic index for McCoy cells by neutral red assay. The synergstic effect was observed when such ...
Environmental relevant levels of the cytotoxic drug cyclophosphamide produce harmful effects in the polychaete Nereis diversicolor
(2018-09-15)
Cytotoxic drugs applied in chemotherapy enter the aquatic environment after patient's metabolism and excretion, in both main compounds and their respective metabolites. The increased consumption and discharge of these drugs ...